The PureLink™ RNA Mini Kit provides rapid purification of total RNA from a wide range of cell and tissue types, including animal, plant, and yeast cells, bacteria, and blood. PureLink™ technology combines guanidine-isothiocyanate lysis with the speed, purity, and ease of use of silica-membrane purification. The safe and easy procedure can be completed in less than 20 minutes without the need for hazardous phenol/chloroform extraction, CsCl centrifugation, or LiCl or alcohol precipitation. High-quality purified RNA can be obtained from mini- to midi-prep amounts of starting material, with minimal genomic DNA contamination. Purified RNA is ready to be used in downstream applications such as RT-PCR, qRT-PCR, northern blots, cDNA synthesis, and nuclease protection assays.